GLENDALE, Ariz. (Interstat) — Drew Lock threw three touchdown passes to Jaxon Smith-Njigba, and Seattle defeated Arizona 31-7 on Sunday, Sept. 20, 2026, at State Farm Stadium. Lock completed 19 of 26 passes for 235 yards. Smith-Njigba finished with nine receptions for 155 yards, scoring on catches of 82, 7 and 12 yards. Emanuel Wilson added 92 rushing yards on 21 carries. Jason Myers made a 33-yard field goal, and AJ Barner scored on a 1-yard direct snap in the fourth quarter. Arizona’s only touchdown came on Jacoby Brissett’s 2-yard pass to Trey McBride. Brissett was 17-of-28 for 95 yards and ran for 7 yards. McBride had eight catches for 41 yards. Seattle’s Leonard Williams recorded six tackles and a sack, while Devon Witherspoon and Ernest Jones IV each made eight tackles. Julian Love intercepted a pass. Budda Baker led Arizona with 11 tackles and a sack. Seattle improved to 2-0, while Arizona dropped to 1-1. Attendance was 63,191. Seattle visits Washington next Sunday, and Arizona visits San Francisco.