GLENDALE, Ariz. (Interstat) — Drew Lock threw three touchdown passes and Jaxon Smith-Njigba caught all three scores as the Seattle Seahawks defeated the Arizona Cardinals 31-7 at State Farm Stadium on Sunday, Sept. 20, 2026. Seattle improved to 2-0. Arizona fell to 1-1. An announced attendance of 63,191 watched the Seahawks take control after an early Arizona response. Seattle finished with 31 points, while Arizona finished with 7.

Lock, a Lee’s Summit, Mo., native listed at 6-foot-4 and 228 pounds, completed 19 of 26 passes for 235 yards and three touchdowns. Smith-Njigba, a Rockwall, Texas, native listed at 6-foot and 197 pounds, had nine receptions for 155 yards and three touchdowns. Cooper Kupp, a Yakima, Wash., native listed at 6-foot-2 and 208 pounds, added two receptions for 20 yards. Elijah Arroyo had one reception for 17 yards. Eric Saubert had one reception for minus-10 yards. AJ Barner had one reception for 8 yards and scored on a 1-yard run. Rashid Shaheed, a San Diego native listed at 6-foot and 180 pounds, had three receptions for 35 yards, one run for 4 yards, two kick returns for 47 yards and three punt returns for 29 yards. Emanuel Wilson, a Charlotte, N.C., native listed at 5-foot-11 and 226 pounds, led Seattle with 21 carries for 92 yards. Jadarian Price added 13 carries for 52 yards and one reception for 8 yards. George Holani had four carries for 13 yards, one reception for 2 yards and one tackle. Jason Myers made his only field goal attempt, a 33-yard kick, and added four extra points. Michael Dickson punted twice for 93 yards. Blake Gillikin of Arizona punted seven times for 289 yards.

Seattle’s defense held Arizona to one touchdown. Leonard Williams, a Daytona Beach, Fla., native listed at 6-foot-5 and 302 pounds, had six tackles and one sack. Jarran Reed had one tackle and one sack. Devon Witherspoon, a Pensacola, Fla., native listed at 6-foot and 185 pounds, and Ernest Jones IV, a Waycross, Ga., native listed at 6-foot-2 and 230 pounds, each had eight tackles. Drake Thomas had seven tackles. Julian Love, a Westchester, Ill., native listed at 5-foot-11 and 195 pounds, had three tackles and one interception. Rylie Mills had four tackles. Byron Murphy II had two tackles. Josh Jobe, AJ Finley, Julian Neal, Nick Emmanwori, Avery Smith, Uchenna Nwosu, Nehemiah Pritchett and Derick Hall each had one tackle. Chazz Surratt, DeMarcus Lawrence and Rodney Thomas II did not record a tackle. Arizona was led by Budda Baker with 11 tackles and one sack. Mack Wilson Sr. and Jack Gibbens each had nine tackles. Andrew Wingard had eight tackles. Dante Stills had seven tackles. Darius Robinson had six tackles. Zaven Collins had five tackles. Roy Lopez and Jordan Burch each had four tackles. Devin Duvernay had one kick return for 40 yards.

Jacoby Brissett, a West Palm Beach, Fla., native listed at 6-foot-4 and 235 pounds, completed 17 of 28 passes for 95 yards and one touchdown for Arizona. He also had a 7-yard run. Trey McBride, a Fort Morgan, Colo., native listed at 6-foot-3 and 249 pounds, caught eight passes for 41 yards and the touchdown. Jeremiyah Love ran nine times for 29 yards and caught three passes for 16 yards. Bam Knight had two carries for 24 yards. Tyler Allgeier had five carries for 10 yards and two receptions for 9 yards. Michael Wilson caught two passes for 18 yards. Kendrick Bourne caught two passes for 11 yards. Marvin Harrison Jr. did not record a catch.

Seattle opened the scoring in the first quarter when Lock connected with Smith-Njigba on a deep right pass for an 82-yard touchdown. Myers made the extra point for a 7-0 lead. Arizona answered in the second quarter when Brissett found McBride on a short left pass for a 2-yard touchdown. Ryland added the extra point to tie the game at 7. In the third quarter, Lock hit Smith-Njigba on a short middle pass for a 7-yard touchdown, and Myers made the extra point for a 14-7 lead. Myers then made a 33-yard field goal for a 17-7 advantage. In the fourth quarter, Lock found Smith-Njigba again on a short middle pass for a 12-yard touchdown, and Myers made the extra point for a 24-7 lead. With 1:11 remaining, Barner took a direct snap and scored on a 1-yard run up the middle. Myers made the extra point to cap the scoring at 31-7.

Seattle had opened the season with a 13-10 win over New England on Sept. 9. Arizona had opened with a 26-14 win at the Los Angeles Chargers on Sept. 13. Seattle next visits Washington on Sept. 27. The Seahawks then host the Los Angeles Chargers on Oct. 4 and San Francisco on Oct. 11 before visiting Denver on Oct. 15. They host Kansas City on Oct. 25, Chicago on Nov. 2 and Arizona on Nov. 8. They visit Las Vegas on Nov. 15 and San Francisco on Nov. 29 before hosting Dallas on Dec. 7. Arizona next visits San Francisco on Sept. 27 and the New York Giants on Oct. 4 before hosting Detroit on Oct. 11. The Cardinals visit the Los Angeles Rams on Oct. 18, host Denver on Oct. 25, visit Dallas on Nov. 1 and Seattle on Nov. 8, host the Los Angeles Rams on Nov. 15, visit Kansas City on Nov. 22 and host Washington on Nov. 29.

Interstat’s game simulator projected Arizona 28, Seattle 24. Interstat’s ELO system gave Seattle a 95.4 percent pregame probability to win. Arizona was installed as a pregame favorite with a spread of minus 3.5. The over/under line was 40.5, and the game total was 38.