INDIANAPOLIS (Interstat) — Lamar Jackson threw for 324 yards and a touchdown and ran for another, Derrick Henry rushed for 144 yards and three touchdowns, and Baltimore defeated Indianapolis in an NFL season opener at Lucas Oil Stadium on Sunday, Sept. 13, 2026. Zay Flowers caught five passes for 150 yards and one touchdown. Baltimore improved to 1-0, while Indianapolis dropped to 0-1. Daniel Jones passed for 166 yards and one touchdown for the Colts. Jonathan Taylor rushed for 98 yards and two touchdowns and added three receptions for 23 yards. Tyler Warren caught a 9-yard touchdown. Roquan Smith made 11 tackles and intercepted a pass, Malaki Starks recorded seven tackles and one sack, and Trenton Simpson had four tackles for Baltimore. Justin Walley made six tackles, Akeem Davis-Gaither had eight, Cam Bynum, A.J. Haulcy and Bryce Boettcher each had seven for Indianapolis. Rigoberto Sanchez punted five times for 263 yards. The Ravens led throughout after an early Colts touchdown, and Tyler Loop made field goals of 57 and 45 yards. Attendance was 65,045.