GLENDALE, Ariz. (Interstat) — The San Francisco 49ers built a commanding early lead and cruised to a 41-22 victory over the Arizona Cardinals on Sunday at State Farm Stadium. Brock Purdy threw three touchdown passes, two to George Kittle, and Christian McCaffrey added two rushing scores for the 49ers.

San Francisco dominated the first half, scoring on its first two possessions and leading 25-10 at halftime. The 49ers improved to 7-4. Jacoby Brissett passed for 452 yards and two touchdowns for the Cardinals, who fell to 3-7. Michael Wilson caught 15 passes for 185 yards in the loss for Arizona. Attendance was 65,032.