DENVER (Interstat) — The Cincinnati Bengals will look to rebound from a humbling defeat when they visit the Denver Broncos for a Monday night matchup on Sept. 29, 2025, at Dick’s Sporting Goods Park.

Cincinnati (2-1) arrives in Denver after a 48-10 road loss to the Minnesota Vikings last Sunday. Quarterback Jake Browning completed 19 of 27 passes for 140 yards and a touchdown in the loss. The Bengals started the season with narrow victories over Cleveland and Jacksonville but were thoroughly outplayed in Minneapolis.

The Denver Broncos (1-2) are also seeking to get back on track following a pair of close losses. They fell 23-20 to the Los Angeles Chargers last week. Rookie quarterback Bo Nix, who rushed for 33 yards and a touchdown in the game, will face a Bengals defense that surrendered 48 points.

Despite their recent results, the Bengals have been installed as a 7.5-point favorite by oddsmakers. The over/under is set at 44.5 points. However, Interstat’s game simulator projects an upset, forecasting a 32-22 victory for the Broncos.

The prime-time contest offers both teams a critical opportunity to build momentum before navigating challenging schedules. Following this game, Cincinnati hosts Detroit, while Denver travels to face Philadelphia.