CHICAGO (Interstat) — Caleb Durbin hit a two-run homer in the fourth inning, and the Boston Red Sox defeated the Chicago White Sox 2-1 on Thursday afternoon at Guaranteed Rate Field.

Durbin’s blast to left field scored Romy Gonzalez, giving Boston a 2-0 lead. The White Sox answered in the fifth when Andrew Benintendi’s soft groundout to catcher Connor Wong drove in Luisangel Acuña, cutting the margin to 2-1.

Boston starter Patrick Sandoval allowed one earned run on five hits with five strikeouts over 4⅓ innings. Tyron Guerrero (1-1) earned the win with 1⅔ innings of relief, allowing two hits and striking out one. Aroldis Chapman pitched a perfect ninth for his 19th save.

Chicago’s Anthony Kay (6-4) took the loss, giving up two earned runs on four hits over 5⅓ innings while striking out four. Jordan Hicks tossed 1⅔ scoreless innings for the White Sox.

Boston improved to 43-48 with its third straight win in the series, while Chicago fell to 47-45. The Red Sox totaled four hits; the White Sox had seven. The game lasted 2 hours, 32 minutes in front of 19,148 fans.