SAN FRANCISCO (Interstat) — Jonatan Clase homered and drove in three runs, and the Toronto Blue Jays erupted for eight runs over the second and third innings to beat the San Francisco Giants 9-3 on Tuesday night at Oracle Park.

The victory snapped a two-game losing streak for Toronto, which improved to 43-49. San Francisco fell to 38-53 with its second straight loss.

Clase’s three-run homer in the top of the second inning opened the scoring and provided the decisive blow. The left fielder connected off Giants starter Trevor McDonald, sending a fly ball to right field that cleared the wall and scored Brandon Valenzuela and Sean Keys, who had singled earlier in the frame. Toronto added a third run in the inning when Ernie Clement doubled but was stranded.

The Blue Jays broke the game open in the third inning with a five-run outburst. Vladimir Guerrero Jr. and Kazuma Okamoto led off with singles, and Valenzuela singled to drive in Guerrero. After a groundout moved runners to second and third, Keys singled to right field, scoring Okamoto and Valenzuela. Clase followed with a single, and Andrés Giménez delivered a line-drive single to left that scored Keys. Clement added a sacrifice fly to right to bring home Clase, making it 8-1.

San Francisco had answered in the bottom of the second with a run on Victor Bericoto’s RBI single, but the Giants never recovered from the early deficit. They added single runs in the third and fifth innings. In the third, Heliot Ramos singled, took third on a double play grounder by Rafael Devers and scored on the same play. In the fifth, Ramos singled and scored on Luis Arraez’s double.

Toronto’s bullpen held the Giants in check after starter Spencer Miles allowed two runs over four innings. Miles gave up seven hits and struck out one but was lifted after allowing three consecutive singles to start the fourth. The Blue Jays used five relievers, with Patrick Corbin picking up the win. Corbin pitched 2⅓ innings, allowing one earned run on two hits with two strikeouts. Mason Fluharty worked a scoreless seventh with a strikeout, Jeff Hoffman recorded two outs in the eighth, and Louis Varland closed out the ninth with a strikeout.

The Giants’ most effective pitcher was Adrian Houser, who entered in the third inning after McDonald was removed. Houser threw 5⅔ hitless innings, striking out five and walking none. He allowed no runs and faced the minimum over that stretch, but the damage had already been done. McDonald took the loss, charged with eight runs on nine hits over 2⅔ innings.

Toronto outhit San Francisco 13-9. Clement went 3-for-4 with an RBI and a double. Valenzuela had two hits and an RBI, and Keys also collected two hits and two RBIs. Arraez and Ramos each had two hits for the Giants.

Defensive miscues were few, but Toronto grounded into two double plays, both involving Vladimir Guerrero Jr. The first ended the top of the first inning with runners on first and second, and the second ended the top of the ninth with Toronto holding a 9-3 lead.

The game was played in front of 32,140 fans and lasted 2 hours, 26 minutes.

Toronto had lost the opener of the three-game series 10-1 on Monday and had dropped three of its previous four games overall. The Blue Jays have struggled on the road, but the early outburst provided a welcome change. San Francisco had won four of its previous six before Monday’s rout but could not sustain momentum.

The win evened the season series at one game apiece with the finale scheduled for Wednesday.

Interstat’s game simulator had projected a final score of San Francisco 4, Toronto 3. Interstat’s ELO system gave Toronto a 52.70 percent probability to win. Toronto was installed as a pregame favorite with a spread of minus-1½. The total score of 12 went under the over-under line of 7½.