PITTSBURGH (Interstat) — Mickey Moniak drove in five runs with a home run, a triple and a double, leading the Colorado Rockies to a 10-4 victory over the Pittsburgh Pirates on Wednesday night at PNC Park.

The Rockies, who had lost the opener of the three-game series 3-1 the previous night, broke open a close game with a six-run fifth inning and added three more in the ninth. Colorado improved to 17-26, while Pittsburgh fell to 23-20.

Moniak, who entered the game in a 2-for-12 slump over his previous four games, went 3 for 5 with a three-run homer in the fifth and a two-run triple in the ninth. He also doubled in the eighth and scored twice.

The Pirates took a 2-0 lead in the second inning. Ryan O’Hearn doubled and scored on a fielder’s choice by Henry Davis, who also drove in Nick Gonzales after Gonzales had walked. A second run scored on the same play when pitcher Jose Quintana was charged with an interference error.

Pittsburgh added a run in the third on an RBI single by Bryan Reynolds, making it 3-0. O’Hearn homered in the sixth to get the Pirates within 10-4, but that was their final run.

Colorado tied the game with its outburst in the fifth. TJ Rumfield singled, Troy Johnston singled and Kyle Karros singled to load the bases with no outs. Karros’ hit scored Rumfield. Jake McCarthy doubled to score Johnston, and Ezequiel Tovar singled to score Karros. With runners on first and third and one out, Moniak homered to right field, scoring Tovar and Brett Sullivan, who had reached on a fielder’s choice. The inning put Colorado ahead 6-3.

The Rockies added a run in the eighth. Moniak doubled, moved to third on a sacrifice bunt by Tyler Freeman and scored on a homer by Rumfield, his sixth of the season.

In the ninth, Colorado padded the lead. Brenton Doyle singled, Tovar walked and Sullivan reached on a fielder’s choice with a throwing error by Pittsburgh pitcher Justin Lawrence, allowing Doyle to score. Moniak then tripled to center, scoring Tovar and Sullivan.

Antonio Senzatela earned the win, pitching three innings in relief of starter Jose Quintana. Senzatela allowed one run on one hit while striking out two. He improved to 3-0. Quintana started and threw four innings, allowing five hits and two earned runs with two strikeouts. Jaden Hill pitched a perfect seventh inning with one strikeout, and Brennan Bernardino closed with a scoreless ninth.

Mitch Keller took the loss for Pittsburgh, falling to 4-2. He worked 5 2/3 innings, giving up seven hits and six earned runs while striking out three. Justin Lawrence pitched the eighth and allowed two hits and one unearned run. Evan Sisk struck out two in 1 1/3 scoreless innings.

O’Hearn led the Pirates with two hits, including his sixth homer, and drove in one run. Reynolds had a single and an RBI. Pittsburgh managed only six hits overall.

The game turned decisively in Colorado’s fifth inning, when the Rockies sent 10 batters to the plate and erased a 3-0 deficit. Moniak’s three-run homer was the big blow, but the inning started with three consecutive singles and a double before the home run. The Rockies batted around and took a lead they would not relinquish.

Colorado’s offense finished with 11 hits. Rumfield went 3 for 4 with a home run and an RBI. Karros had two hits and an RBI. Tovar had two hits and an RBI, and McCarthy doubled and drove in a run.

Pittsburgh starter Keller struggled with command early but settled in until the fifth. He walked two and struck out three. The Pirates’ bullpen held the Rockies scoreless in the sixth and seventh but could not contain them in the late innings.

Attendance was 10,554. The game lasted 2 hours, 29 minutes.

The Rockies are scheduled to play the Pirates again Thursday in the series finale before returning home to host Arizona on Friday. The Pirates will host Philadelphia on Friday after the series with Colorado concludes.

Interstat’s game simulator projected a final score of Pittsburgh 5, Colorado 2. Interstat’s ELO system gave the Pirates a 69.10 percent probability of winning. Pittsburgh was installed as a pregame favorite with a spread of minus 1.5 runs. The total score of 14 went under the over/under line of 8 runs.