MILWAUKEE (Interstat) — Jacob Misiorowski reached triple digits with clocked 103 mph on 10 pitches while firing two-hit ball over six innings and Brandon Lockridge drove in two runs before being carted off with a knee injury, leading the Milwaukee Brewers to a 6-0 shutout of the New York Yankees on Friday night at American Family Field.

Misiorowski, who touched 103.6 mph, struck out 11 and walked two in his second straight dominant start. He carried a no-hit bid into the sixth inning last week before a hamstring cramp forced him out. This time he allowed only a single and a double while never letting a Yankees runner reach third base. The right-hander lowered his ERA and improved to 3-2, striking out the side in the first and fifth innings.

The Brewers broke the game open with a four-run second inning off Yankees left-hander Max Fried. Gary Sanchez started the rally with a leadoff single, and Andrew Vaughn and Luis Rengifo drew walks to load the bases. Lockridge then singled to right to score Sanchez, and Sal Frelick followed with a line-drive single to center that plated Vaughn. Joey Ortiz grounded into a force out that brought home Rengifo, and Jackson Chourio singled to center to score Lockridge, giving Milwaukee a 4-0 lead.

Milwaukee added a run in the third. Vaughn led off with a ground-rule double to center and scored on Lockridge’s second RBI single, a line drive to center. Lockridge left the game in the fourth inning after crashing into an unpadded section of the left-field wall while chasing a foul ball off the bat of Cody Bellinger. He was carted off with an apparent right knee injury, finishing 2 for 2 with two RBIs.

The final Brewers run came in the seventh against reliever Kervin Castro. Joey Ortiz doubled to center with one out, advanced to third on a groundout by Brice Turang and scored on a single by William Contreras.

Misiorowski’s only blemish through the first five innings was a two-out single by Jose Caballero in the third. He also surrendered a one-out double to Vaughn in the third before settling in. He allowed just one more hit, a single by Austin Wells in the fifth, before departing after six innings. Shane Drohan relieved and closed the game with three scoreless innings, allowing one hit and striking out three to earn his first save.

Fried took the loss, falling to 4-2. He worked six innings and allowed six hits and five earned runs while striking out five and walking three. The left-hander struggled to command his fastball, issuing two walks in the second inning that led to the big rally. He retired the side in order only in the fourth and fifth innings.

The Yankees managed just three hits in the game. Caballero went 2 for 3 with a walk, and Aaron Judge singled in the ninth inning for New York’s only other hit. Judge struck out in his first three at-bats, and the top of the order combined to go 1 for 15 with seven strikeouts. Six Yankees hitters struck out multiple times as Milwaukee pitchers racked up 14 strikeouts total.

Milwaukee’s offense was led by Contreras, who went 1 for 4 with an RBI, and Chourio, who singled and drove in a run. Vaughn doubled and scored twice, Frelick singled and drove in a run, and Ortiz doubled and knocked in a run. The Brewers finished with eight hits and drew three walks.

The game lasted 2 hours, 24 minutes in front of an announced crowd of 38,051.

New York entered with a 26-13 record, the best in the American League, having won 10 of its previous 11 games. Milwaukee improved to 20-16, winning for the fifth time in six games. The Brewers had lost four straight before that stretch.

Misiorowski’s recent outings include a 5 1/3-inning no-hit effort against Washington on May 1 and a six-inning, three-run performance against Pittsburgh on April 25.

Interstat’s game simulator had projected a final score of New York Yankees 7, Milwaukee Brewers 5. The ELO system gave the Yankees a 50.30 percent probability to win. New York had been installed as a pregame favorite with a spread of minus 1.5 runs. The total score of six runs went over the over-under line of seven.