BOSTON (Interstat) — The San Diego Padres defeated the Boston Red Sox 8-6 on Sunday, April 5, 2026, securing a series win at Fenway Park. San Diego rallied with three runs in both the fourth and fifth innings, highlighted by a three-run homer from Manny Machado. Boston’s four-run third, fueled by a two-run double from Jarren Duran and RBI hits from Wilyer Abreu and Masataka Yoshida, proved insufficient. Yoshida drove in three for Boston. Jeremiah Estrada earned the win in relief for the 4-5 Padres. Tyler Uberstine took the loss for the 2-7 Red Sox. Mason Miller struck out the side in the ninth for his fourth save. Attendance was 29,240.