St. Louis Cardinals at Detroit Tigers

Preview: Cardinals at Tigers, Saturday, April 4, 2026

DETROIT (Interstat) — The St. Louis Cardinals look to even their series with the Detroit Tigers on Saturday afternoon at Comerica Park after being shut out in the opener.

First pitch is scheduled for 1:10 p.m. EDT under cloudy skies with temperatures around 70 degrees.

The Cardinals (4-3) were held to three hits in a 4-0 loss on Friday. The Tigers (3-4) used a strong start from Framber Valdez and a two-run homer from Dillon Dingler to secure the win.

Saturday’s pitching matchup features a pair of right-handers seeking their first win. The Cardinals are expected to start Jack Flaherty (0-1), while the Tigers counter with Dustin May (0-1). Both pitchers took losses in their season debuts.

A player to watch for St. Louis is Michael McGreevy, who started Friday’s loss. He allowed three runs over 4 2/3 innings but is coming off a stellar six-inning, no-hit performance against Tampa Bay on March 28.

For Detroit, Valdez is a key figure even after pitching Friday. His dominant outing set the tone for the series and highlighted a Tigers rotation that has shown flashes of strength early.

Despite the Tigers’ victory, statistical projections are split. Interstat’s game simulator predicts a 6-2 Cardinals victory, while its ELO rating system gives Detroit a 57.1% probability to win. Betting markets list the Tigers as a -1.5 run favorite with an over/under of 7.5 total runs.

The Cardinals’ offense, which averaged over five runs per game in their first six contests before being blanked, will aim to rebound against May. The Tigers have won two straight after a four-game skid.

Following Saturday’s game, the series concludes Sunday before both teams embark on road trips. The Cardinals head to Washington for three games, while the Tigers travel to Minnesota for a four-game set.