WASHINGTON (Interstat) — The Chicago White Sox and Washington Nationals will continue their three-game series Saturday evening at Nationals Park after the White Sox claimed the opener 8-5 on Friday.

First pitch is scheduled for Saturday, Sept. 27, 2025, under cloudy skies with a game-time temperature of 82 degrees.

The matchup features two pitchers with losing records. The White Sox (58-101) will send right-hander Sean Burke (4-11) to the mound. He will be opposed by Nationals right-hander Jake Irvin (9-13).

Chicago arrives having lost eight of its last 10 games, including a 5-3 loss to the New York Yankees on Thursday. The Nationals (65-94) have been more competitive lately, winning three of their last five contests. Their most recent game was a 4-3 victory over the Atlanta Braves on Wednesday, powered by a two-home run performance from designated hitter James Wood.

According to Interstat’s game simulator, Washington is projected to win 3-1. Betting markets favor the Nationals with a -1.5 spread, and the over/under for total runs is set at 8.5.

The series concludes Sunday.