OXFORD, Miss. (Interstat) — A struggling Florida team aims to play spoiler on the road Saturday as it visits Ole Miss, which looks to keep its College Football Playoff hopes alive.

The Gators (3-6) are reeling from a 38-7 loss at Kentucky last Saturday, a game where they used three different quarterbacks. DJ Lagway, Tramell Jones Jr. and AJ Maddox all saw action, combining for a meager 162 passing yards. The defeat continued a difficult season for Florida, which has lost six of its last eight games.

Conversely, the Rebels (9-1) are rolling after a 49-0 rout of The Citadel. Quarterback Trinidad Chambliss was efficient, completing 29 of 33 passes for 333 yards and three touchdowns. Ole Miss’s lone blemish is a 43-35 loss to Georgia on Oct. 18, and they remain in the hunt for an SEC championship berth.

Despite the stark contrast in records, Interstat’s game simulator projects a tight contest, with Ole Miss favored 25-24. However, oddsmakers see a wider margin, installing the Rebels as 13.5-point favorites. The over/under is set at 54.5.

The game is scheduled for Saturday, Nov. 15, 2025, at Vaught-Hemingway Stadium.