NORMAN, Okla. (Interstat) — A clash of Southeastern Conference powers headlines the Week 9 college football slate as the Oklahoma Sooners host the Ole Miss Rebels on Saturday at Memorial Stadium.

The Rebels (6-0) arrive in Norman as one of the nation’s few remaining undefeated teams, though they are coming off their first true test, a 43-35 road loss to Georgia. Quarterback Trinidad Chambliss leads an explosive Ole Miss offense, accounting for over 300 total yards and three touchdowns in the defeat.

Oklahoma (5-1) has rebounded strongly since a 23-6 loss to Texas, most recently dominating South Carolina 26-7 on the road. The Sooners’ defense has been stifling, while the ground game, led by Tory Blaylock’s 101-yard effort last week, provides balance.

Despite Ole Miss’s unblemished record, oddsmakers list the Rebels as a 4.5-point underdog. The over/under is set at 54.5. A projection from Interstat favors the Sooners, 33-20.

The game is a critical matchup for conference positioning and the College Football Playoff landscape. Oklahoma will look to defend its home field and secure a signature win, while Ole Miss aims to prove its perfect start is no fluke against a top-tier opponent.