- 2025-11-24 10mo Carolina Panthers 9 at San Francisco 49ers 20 Brock Purdy SFF 23/32-193yd 6run-16yd 1td
- 2022-10-09 4y San Francisco 49ers 37 at Carolina Panthers 15 Jimmy Garoppolo SFF 18/30-253yd 2td
- 2019-10-27 6y Carolina Panthers 13 at San Francisco 49ers 51 Jimmy Garoppolo SFF 18/22-175yd 2td
- 2017-09-10 9y Carolina Panthers 23 at San Francisco 49ers 3 Cam Newton CAR 14/25-171yd 6run-3yd 1tck 2td
- 2016-09-18 10y San Francisco 49ers 27 at Carolina Panthers 46 Cam Newton CAR 24/40-353yd 6run-37yd 4td
- 2014-01-12 12y San Francisco 49ers 23 at Carolina Panthers 10 Colin Kaepernick SFF 15/28-196yd 8run-15yd 1td 1td
- 2013-11-10 12y Carolina Panthers 10 at San Francisco 49ers 9 Cam Newton CAR 16/32-169yd 8run-15yd
- 2010-10-24 15y San Francisco 49ers 20 at Carolina Panthers 23 Matt Moore CAR 28/41-308yd 1run-3yd 2td
- 2007-12-02 18y San Francisco 49ers 14 at Carolina Panthers 31 Vinny Testaverde CAR 17/26-169yd 2td
- 2004-11-14 21y Carolina Panthers 37 at San Francisco 49ers 27 Jake Delhomme CAR 19/34-303yd 3td
- 2001-11-18 24y San Francisco 49ers 25 at Carolina Panthers 22 Jeff Garcia SFF 34/54-305yd 1run-1yd 3td
- 2001-10-07 25y Carolina Panthers 14 at San Francisco 49ers 24 Jeff Garcia SFF 17/31-212yd 3run-20yd 2td 1td
- 2000-10-22 25y San Francisco 49ers 16 at Carolina Panthers 34 Steve Beuerlein CAR 28/44-309yd 2run-3yd 3td
- 2000-09-10 26y Carolina Panthers 38 at San Francisco 49ers 22 Steve Beuerlein CAR 24/32-364yd 3td
- 1999-12-18 26y San Francisco 49ers 24 at Carolina Panthers 41
- 1999-10-17 26y Carolina Panthers 31 at San Francisco 49ers 29
- 1998-12-06 27y San Francisco 49ers 31 at Carolina Panthers 28
- 1998-11-08 27y Carolina Panthers 23 at San Francisco 49ers 25
- 1997-11-16 28y Carolina Panthers 19 at San Francisco 49ers 27
- 1997-09-29 29y San Francisco 49ers 34 at Carolina Panthers 21
- 1996-12-08 29y Carolina Panthers 30 at San Francisco 49ers 24
- 1996-09-22 30y San Francisco 49ers 7 at Carolina Panthers 23
- 1995-12-10 30y San Francisco 49ers 31 at Carolina Panthers 10
- 1995-11-05 30y Carolina Panthers 13 at San Francisco 49ers 7