SANTA CLARA (Interstat) — Brock Purdy threw for two touchdowns and ran for another, and San Francisco’s defense returned an interception for a touchdown as the 49ers defeated the Las Vegas Raiders 38-17 on Sunday at Levi’s Stadium. The National Football League game drew an announced attendance of 71,753.

Purdy, a Gilbert, Ariz., native, completed 17 of 25 passes for 232 yards and ran seven times for 40 yards. Christian McCaffrey carried 18 times for 68 yards and caught two passes for 19 yards, scoring both on the ground and through the air. Jordan Watkins had four receptions for 86 yards and a touchdown. George Kittle added four catches for 58 yards. Demarcus Robinson had three catches for 22 yards. Brandin Cooks had two catches for 25 yards, KhaDarel Hodge had one for 17 yards, Jacob Cowing had one for 5 yards, and Kyle Juszczyk had one run for 4 yards.

Kirk Cousins completed 22 of 32 passes for 216 yards with one touchdown and one interception for Las Vegas. Brock Bowers caught seven passes for 111 yards and a touchdown and added one run for 2 yards. Tre Tucker had four catches for 55 yards. Michael Mayer had three receptions for 37 yards. Ashton Jeanty ran six times for 25 yards and caught five passes for minus-5 yards. Jack Bech had one reception for 9 yards and Jalen Nailor had two for 9 yards.

San Francisco scored first when McCaffrey went left guard for a 1-yard touchdown with 9:32 remaining in the opening quarter. Eddy Pineiro added the extra point. Purdy doubled the lead with a 1-yard scramble around right end for a touchdown with 1:52 left in the first. Las Vegas got on the board early in the second when Cousins scored on a 2-yard keeper up the middle, and Matt Gay made the extra point. Purdy then hit McCaffrey for a 12-yard touchdown pass with 5:15 left in the half. Gay made a 50-yard field goal for the Raiders with 1:12 remaining, and San Francisco led 21-10 at halftime.

The 49ers stretched the lead in the third quarter when Cousins was intercepted by Jaden Dugger, who returned the pick 35 yards for a touchdown at 14:43. Las Vegas answered with Cousins’s 21-yard touchdown pass to Bowers down the middle with 9:29 left in the quarter. San Francisco responded when Purdy found Watkins for a 37-yard touchdown pass with 36 seconds remaining in the third. In the fourth quarter, a Cousins pass to Mayer for a 3-yard touchdown was nullified by an offensive pass interference penalty on Mayer. Pineiro made a 35-yard field goal with 5:21 remaining to close the scoring.

Dugger finished with six tackles and an interception return for a touchdown. Dre Greenlaw had eight tackles, Fred Warner had five, and Renardo Green had four tackles and an interception. Upton Stout had four tackles, while Deommodore Lenoir, Osa Odighizuwa, Marques Sigle, Ji’Ayir Brown and Luke Gifford each had three. Malik Mustapha had one tackle and an interception. Brayden Willis had two tackles. DeForest Buckner, Siran Neal, Nick Bosa, Keion White, Connor Colby, Romello Height, Ephesians Prysock and Sebastian Valdez each had one tackle. Pineiro made one field goal. Jordan James had three runs for 11 yards and two kickoff returns for 31 yards.

Las Vegas was led defensively by Nakobe Dean, who had 18 tackles. Quay Walker had 11 tackles and Jeremy Chinn had 10. Tommy Eichenberg added seven tackles. Treydan Stukes had five tackles and an interception. Maxx Crosby had four tackles and a sack. Eric Stokes had four tackles, Tim Keenan III had four tackles and Hezekiah Masses had three. Tre Tucker also had one tackle.

The Raiders fell to 4-5. They had won at the New York Jets in their previous game and will host Seattle next. The 49ers improved to 7-1. Their only loss came at Atlanta, and they will visit Dallas next. San Francisco had won four of its previous five games, including a home victory over Washington.

Interstat’s game simulator projected a final score of San Francisco 45, Las Vegas 21. Interstat’s ELO system gave San Francisco a 95.4 percent probability to win. San Francisco was installed as a pregame favorite with a spread of minus 9, and the total score of 55 was listed against an over/under line of 52.