- 2026-11-29 in 1mo Seattle Seahawks at San Francisco 49ers
- 2026-10-11 4d San Francisco 49ers 32 at Seattle Seahawks 29 Brock Purdy SFF 29/19-189yd 5run-6yd 2td
- 2026-01-17 8mo San Francisco 49ers 6 at Seattle Seahawks 41 Sam Darnold SEA 12/17-124yd 1td
- 2026-01-03 9mo Seattle Seahawks 13 at San Francisco 49ers 3 Sam Darnold SEA 20/26-198yd 6run-9yd
- 2025-09-07 1y San Francisco 49ers 17 at Seattle Seahawks 13 Brock Purdy SFF 26/35-277yd 5run-17yd 2td
- 2024-11-17 1y Seattle Seahawks 20 at San Francisco 49ers 17 Geno Smith SEA 25/32-221yd 4run-29yd 1td
- 2024-10-10 2y San Francisco 49ers 36 at Seattle Seahawks 24 Brock Purdy SFF 18/28-255yd 4run-19yd 3td
- 2023-12-10 2y Seattle Seahawks 16 at San Francisco 49ers 28 Brock Purdy SFF 19/27-368yd 2run-7yd 2td
- 2023-11-23 2y San Francisco 49ers 31 at Seattle Seahawks 13 Brock Purdy SFF 21/30-209yd 3run-1yd 1td
- 2023-01-14 3y Seattle Seahawks 23 at San Francisco 49ers 41 Brock Purdy SFF 4run-16yd 3td 1td
- 2022-12-15 3y San Francisco 49ers 21 at Seattle Seahawks 13 Brock Purdy SFF 2td
- 2022-09-18 4y Seattle Seahawks 7 at San Francisco 49ers 27 Jimmy Garoppolo SFF 13/21-154yd 4run-5yd 1td 1td
- 2021-12-05 4y San Francisco 49ers 23 at Seattle Seahawks 30 Russell Wilson SEA 30/37-231yd 3run-15yd 2td
- 2021-10-03 5y Seattle Seahawks 28 at San Francisco 49ers 21 Russell Wilson SEA 16/23-149yd 4run-26yd 2td 1td
- 2021-01-03 5y Seattle Seahawks 26 at San Francisco 49ers 23 Russell Wilson SEA 20/36-181yd 5run-29yd 2td
- 2020-11-01 5y San Francisco 49ers 27 at Seattle Seahawks 37 Russell Wilson SEA 27/37-261yd 6run-23yd 4td
- 2019-12-29 6y San Francisco 49ers 26 at Seattle Seahawks 21 Jimmy Garoppolo SFF 18/22-285yd 2run-4yd
- 2019-11-11 6y Seattle Seahawks 27 at San Francisco 49ers 24 Russell Wilson SEA 24/34-232yd 6run-53yd 1td
- 2018-12-16 7y Seattle Seahawks 23 at San Francisco 49ers 26 Nick Mullens SFF 20/29-275yd 1td
- 2018-12-02 7y San Francisco 49ers 16 at Seattle Seahawks 43 Russell Wilson SEA 11/17-185yd 4run-14yd 4td
- 2017-11-26 8y Seattle Seahawks 24 at San Francisco 49ers 13 Russell Wilson SEA 20/34-228yd 7run-25yd 2td 1td
- 2017-09-17 9y San Francisco 49ers 9 at Seattle Seahawks 12 Russell Wilson SEA 23/39-198yd 12run-34yd 1td
- 2017-01-01 9y Seattle Seahawks 25 at San Francisco 49ers 23 Russell Wilson SEA 19/32-258yd 2run-4yd 1td
- 2016-09-25 10y San Francisco 49ers 18 at Seattle Seahawks 37 Russell Wilson SEA 15/23-243yd 1run-3yd 1td
- 2015-11-22 10y San Francisco 49ers 13 at Seattle Seahawks 29 Russell Wilson SEA 24/29-260yd 9run-30yd 3td
- 2015-10-22 10y Seattle Seahawks 20 at San Francisco 49ers 3 Russell Wilson SEA 18/24-235yd 7run-20yd 1td
- 2014-12-14 11y San Francisco 49ers 7 at Seattle Seahawks 17 Russell Wilson SEA 12/24-168yd 5run-27yd 1td
- 2014-11-27 11y Seattle Seahawks 19 at San Francisco 49ers 3 Russell Wilson SEA 15/22-236yd 7run-35yd 1td
- 2014-01-19 12y San Francisco 49ers 17 at Seattle Seahawks 23 Russell Wilson SEA 16/25-215yd 1tck 1td
- 2013-12-08 12y Seattle Seahawks 17 at San Francisco 49ers 19 Colin Kaepernick SFF 15/29-175yd 9run-31yd 1td
- 2013-09-15 13y San Francisco 49ers 3 at Seattle Seahawks 29 Russell Wilson SEA 8/19-142yd 10run-33yd 1td
- 2012-12-23 13y San Francisco 49ers 13 at Seattle Seahawks 42 Russell Wilson SEA 15/21-171yd 6run-29yd 4td
- 2012-10-18 13y Seattle Seahawks 6 at San Francisco 49ers 13 Alex Smith SFF 14/23-140yd 5run-11yd 1td
- 2011-12-24 14y San Francisco 49ers 19 at Seattle Seahawks 17 Alex Smith SFF 14/26-179yd 5run-22yd
- 2011-09-11 15y Seattle Seahawks 17 at San Francisco 49ers 33 Alex Smith SFF 15/20-124yd 7run-22yd 1td
- 2010-12-12 15y Seattle Seahawks 21 at San Francisco 49ers 40 Alex Smith SFF 17/27-255yd 4run-12yd 3td
- 2010-09-12 16y San Francisco 49ers 6 at Seattle Seahawks 31 Matt Hasselbeck SEA 18/23-170yd 2run-4yd 2td 1td
- 2009-12-06 16y San Francisco 49ers 17 at Seattle Seahawks 20 Matt Hasselbeck SEA 25/34-198yd 4run-31yd 1tck 2td
- 2009-09-20 17y Seattle Seahawks 10 at San Francisco 49ers 23 Shaun Hill SFF 19/26-144yd 1run-17yd
- 2008-10-26 17y Seattle Seahawks 34 at San Francisco 49ers 13 Seneca Wallace SEA 15/25-222yd 2td
- 2008-09-14 18y San Francisco 49ers 33 at Seattle Seahawks 30 J.T. O'Sullivan SFF 20/32-321yd 4run-32yd 1tck 1td
- 2007-11-12 18y San Francisco 49ers 0 at Seattle Seahawks 24 Matt Hasselbeck SEA 27/40-278yd 6run-16yd 2td
- 2007-09-30 19y Seattle Seahawks 23 at San Francisco 49ers 3 Matt Hasselbeck SEA 23/31-281yd 2td
- 2006-12-14 19y San Francisco 49ers 24 at Seattle Seahawks 14 Alex Smith SFF 14/25-162yd 6run-33yd 2td 1td
- 2006-11-19 19y Seattle Seahawks 14 at San Francisco 49ers 20 Alex Smith SFF 19/25-163yd 1run-1yd 1td 1td
- 2005-12-11 20y San Francisco 49ers 3 at Seattle Seahawks 41 Matt Hasselbeck SEA 21/25-226yd 1run-9yd 4td
- 2005-11-20 20y Seattle Seahawks 27 at San Francisco 49ers 25 Matt Hasselbeck SEA 19/31-233yd 6run-7yd 1td
- 2004-11-07 21y Seattle Seahawks 42 at San Francisco 49ers 27 Matt Hasselbeck SEA 17/28-285yd 3td
- 2004-09-26 22y San Francisco 49ers 0 at Seattle Seahawks 34 Matt Hasselbeck SEA 21/30-254yd 2td
- 2003-12-27 22y Seattle Seahawks 24 at San Francisco 49ers 17 Matt Hasselbeck SEA 24/37-315yd 2td