GLENDALE, Ariz. (Interstat) — Jared Goff threw three touchdown passes and ran for another score as the Detroit Lions beat the Arizona Cardinals 45-21 on Sunday at State Farm Stadium. Detroit improved to 3-2, while Arizona dropped to 1-4. Goff completed 19 of 30 passes for 271 yards. Jahmyr Gibbs ran 25 times for 151 yards and caught five passes for 56 yards and two touchdowns. Jameson Williams caught two touchdown passes, and Sam LaPorta had five receptions for 88 yards and a score. Amon-Ra St. Brown added six catches for 69 yards and two punt returns for 36 yards. Jack Campbell recorded 10 tackles, and DJ Wonnum had two sacks for Detroit. Jacoby Brissett completed 29 of 47 passes for 292 yards and three touchdowns for Arizona. Teagan Quitoriano caught two touchdown passes, and Elijah Higgins had three receptions for 57 yards. Budda Baker made 11 tackles and one sack, while Roy Lopez added six tackles and a sack. Keith Abney II intercepted a pass for Detroit. Attendance at State Farm Stadium was 60,968.