DETROIT (Interstat) — Cade Cunningham had 25 points and 10 assists, Tobias Harris scored 21 points and the Detroit Pistons beat the Cleveland Cavaliers 107-97 on Thursday night to take a 2-0 lead in their second-round playoff series.

Game 3 is Saturday in Cleveland, where the Cavaliers were 4-0 in the first round against Toronto. The top-seeded Pistons have won five straight games since Orlando put them on the brink of elimination in the first round.

Cleveland opened the game with a 3-pointer from Dean Wade, but Detroit responded quickly. Tobias Harris hit a 27-foot three from Cade Cunningham, and Ausar Thompson threw down an alley-oop dunk. Duncan Robinson followed with a 24-foot three, and the Pistons built an early lead. The Cavaliers turned the ball over twice in the first two minutes, and Detroit capitalized.

Donovan Mitchell scored 31 points for Cleveland, but he struggled from long range, hitting just 2 of 11 from three-point range. Jarrett Allen added 22 points and seven rebounds, while Evan Mobley chipped in nine points, four assists and three blocks.

Detroit’s offense was efficient, shooting 14 of 28 from three-point range compared to Cleveland’s 7 of 32. The Pistons also dominated the offensive glass, grabbing 13 offensive rebounds to Cleveland’s nine.

The game featured several key stretches. In the first quarter, Detroit used a 10-2 run to take control. Robinson stole a pass from Jarrett Allen and buried a three, then stole another pass from Evan Mobley and finished a layup. Thompson added a running layup, and the Pistons led 14-3 after just 2:42.

Cleveland fought back behind Mitchell, who scored eight points in the quarter, but Detroit closed the period with a 25-18 lead. Daniss Jenkins scored a driving floater and a dunk off a Cunningham assist, and Caris LeVert hit a 25-foot three.

The Pistons extended their lead in the second quarter. Cade Cunningham hit a 23-foot three, and Jalen Duren scored on a layup. LeVert connected on another three from 26 feet. Detroit led 54-43 at halftime, shooting 52.8 percent from the field.

Cleveland made a push in the third quarter. Mitchell scored 13 points in the period, including a 24-foot three and a 28-foot three. Allen added eight points, and the Cavaliers cut the deficit to 79-76 entering the fourth quarter. But Detroit responded each time. Cunningham scored eight points in the quarter, including two free throws and a fadeaway jumper.

The fourth quarter was tightly contested. Cleveland tied the game at 79-79 on a dunk by Mobley, but Harris answered with a turnaround jumper. Robinson hit a three from 26 feet, and Harris added a driving floater. Detroit led 89-79 with 7:36 left.

Allen scored six straight points for Cleveland, including two free throws and a floating jump shot, to cut the lead to 89-85. Cunningham then hit a 26-foot three, and Harris added another three to push the lead back to 96-89.

Down the stretch, Cunningham sealed the game. He hit a 27-foot step-back three with 2:12 left to make it 101-96. After a Cleveland free throw, Allen scored on a layup to cut the lead to 101-97, but Cunningham missed a driving floater. Ausar Thompson grabbed the offensive rebound and scored on a tip shot to make it 103-97 with 1:22 left.

Mitchell made two free throws to cut the lead to 103-99, but Detroit’s defense held. Cunningham made two free throws with 22.7 seconds left to seal the victory.

Key performances included Cunningham, who played 42 minutes and added four rebounds and two blocks. Harris played 37 minutes and grabbed seven rebounds with two blocks. Robinson scored 17 points on 5-of-10 shooting from three. Daniss Jenkins had 14 points, six rebounds and four assists off the bench. Ausar Thompson contributed 10 points, seven rebounds and two assists.

For Cleveland, Jarrett Allen shot 8 of 12 from the field and grabbed seven rebounds. Donovan Mitchell had six rebounds and three assists but shot 10 of 27 from the field. Evan Mobley added nine points and four assists. Dean Wade scored eight points with five rebounds.

The Pistons shot 39 of 80 from the field, 14 of 28 from three and 15 of 20 from the free-throw line. The Cavaliers shot 34 of 81 from the field, 7 of 32 from three and 22 of 27 from the free-throw line. Detroit had 13 offensive rebounds to Cleveland’s nine. The Pistons committed 10 turnovers, while the Cavaliers committed 11.

The most important part of the game came in the final three minutes. With Cleveland trailing 96-94 after Allen’s layup, Cunningham hit a 27-foot three to give Detroit a five-point lead. After a Cleveland miss, Cunningham blocked a three-point attempt by Max Strus. Thompson then grabbed an offensive rebound and scored on a tip shot to push the lead to six. Cleveland never got closer than four points the rest of the way.

Cunningham’s performance continued his strong playoff run. He had 23 points and seven assists in Game 1 against Cleveland, and he had 32 points and 12 assists in a series-clinching win over Orlando.

The Cavaliers have lost two straight after winning four in a row in the first round. Cleveland had a 56-35 regular-season record, while Detroit finished 66-25.

The series shifts to Cleveland for Games 3 and 4. The Cavaliers were 4-0 at home in the first round.

Interstat’s game simulator had projected a final score of Detroit 118, Cleveland 106. Interstat’s ELO system projected Detroit with an 80.60 percent probability to win. Detroit was installed as a pregame favorite with a spread of minus 3.5. The total score of 204 went under the over/under line of 215.5.