ST. LOUIS (Interstat) — Jacob Misiorowski struck out 11 over seven innings and Christian Yelich drove in two runs to lift the Milwaukee Brewers to a 4-3 victory over the St. Louis Cardinals in the first game of a doubleheader Tuesday afternoon at Busch Stadium III.

The Brewers, who entered with the best record in the National League at 57-33, won their second straight game against the Cardinals after a 4-3 victory Monday. Milwaukee improved to 4-2 in the season series. The Cardinals fell to 47-42.

Misiorowski, who earned his 10th win against four losses, allowed three hits and three earned runs while walking none. He struck out the side in the second inning and fanned at least two in four of his seven frames. The right-hander retired 10 of the final 11 batters he faced, including six consecutive strikeouts from the fourth into the sixth inning.

Abner Uribe pitched a scoreless ninth inning, allowing no hits and striking out one, to earn his sixth save. Uribe induced a groundout to end the game with the tying run on base.

Ryne Stanek took the loss for St. Louis, falling to 2-2. He pitched one inning, allowing one run on one hit with one walk and one strikeout.

The Cardinals struck first in the bottom of the first inning. JJ Wetherholt was hit by a pitch and moved to second on a groundout. Jordan Walker then launched his 21st home run of the season, a fly ball to left field that scored Wetherholt and gave St. Louis a 2-0 lead. Lars Nootbaar followed with a double, but Misiorowski stranded him with a strikeout.

Milwaukee answered in the third inning. Cooper Pratt drew a walk and scored on a double by Joey Ortiz, who lofted a line drive to left field. Christian Yelich followed with a sharp single to center field that brought home Ortiz, tying the game 2-2. The Brewers were unable to add more as Jackson Chourio grounded into a double play and Brice Turang struck out.

St. Louis regained the lead in the bottom of the third. Ivan Herrera led off with a solo home run to left field, his 11th of the season, making it 3-2. Misiorowski retired the next three batters in order.

The Brewers tied the game again in the sixth inning. Jake Bauers led off with a double to right field, his second of the game. Garrett Mitchell singled to center field, scoring Bauers, and Mitchell advanced to second on the throw. The call was upheld after a Cardinals challenge on a tag play at the plate. Mitchell was left stranded as Sal Frelick grounded out.

Milwaukee took the lead for good in the seventh inning. Pratt again walked to start the frame. Ortiz laid down a bunt single to first base, moving Pratt to second. Yelich then ripped a double down the left-field line, scoring Pratt and sending Ortiz to third. Yelich finished the game 3 for 5 with two doubles and two runs batted in. The Brewers loaded the bases later in the inning on an intentional walk to William Contreras, but Andrew Vaughn grounded out to end the threat.

The Cardinals put a runner in scoring position in the eighth inning. Wetherholt singled with two outs and Herrera followed with a single, but Alec Burleson grounded into a forceout to extinguish the rally.

In the ninth, Jordan Walker popped out. Nootbaar walked, but Bryan Torres struck out and Nathan Church grounded out to seal the Brewers’ victory.

Milwaukee pounded out 10 hits, with Ortiz collecting three hits and scoring a run. Yelich had three hits and two RBIs. Bauers had two doubles. The Brewers also drew three walks, including two by Pratt.

St. Louis managed only five hits. Herrera had two hits, including his solo homer. Walker drove in two runs with his home run. Wetherholt had a hit and was hit by a pitch. The Cardinals struck out 13 times.

Bruce Zimmermann started for St. Louis and worked five innings, allowing six hits and three earned runs with two strikeouts. Justin Bruihl pitched two scoreless innings of relief, allowing one hit and striking out one. JoJo Romero and Matt Svanson each threw a scoreless inning of relief.

The game marked the first contest of a scheduled doubleheader, with the second game set to begin later Tuesday evening. The attendance was 24,422, and the game lasted 2 hours, 38 minutes.

Interstat’s game simulator had projected a final score of Milwaukee Brewers 6, St. Louis Cardinals 5. Interstatl’s ELO system had projected Milwaukee with a 58.80 percent probability to win. Milwaukee had been installed as a pregame favorite with a spread of minus 1.5 runs. The total score of 7 went over the over/under line of 7.5.