SAN FRANCISCO (Interstat) — The Minnesota Twins will visit the San Francisco Giants on Wednesday, Sept. 23, 2026, at Oracle Park in San Francisco. Minnesota is the visiting team and enters at 73-84. San Francisco is the home team and enters at 65-92. Cesar Perdomo is the probable pitcher for Minnesota and has a season record of 0-1. The forecast calls for 64-degree weather at game time.

Travis Adams is a player to watch for Minnesota. On Sept. 21 at San Francisco, he pitched 1.2 innings with one hit, no earned runs and three strikeouts. He pitched one inning with no hits and no earned runs Sept. 18 at the Los Angeles Angels. Against the New York Yankees on Sept. 16, Adams worked three innings, allowed two hits and no earned runs, and struck out one. He gave up two earned runs on four hits in three innings Sept. 13 against Cleveland. On Sept. 9 at Detroit, he pitched 2.2 innings with one hit, no earned runs and three strikeouts. He allowed one earned run on one hit in 2.1 innings Aug. 28 against the Chicago White Sox.

Drew Gilbert is a player to watch for San Francisco. He went 3 for 4 with one home run and three RBIs Sept. 21 against Minnesota. Gilbert also went 1 for 1 with one home run and two RBIs Sept. 16 at St. Louis and 2 for 4 with one home run and two RBIs Sept. 12 against San Diego. He had hitless appearances Sept. 20 at the Los Angeles Dodgers, Sept. 18 at Los Angeles, Sept. 15 at St. Louis, Sept. 13 against San Diego and Sept. 11 against San Diego.

The teams have split the first two games of the series. Minnesota won 3-1 on Tuesday, Sept. 22. San Francisco won 5-2 on Monday, Sept. 21. In that Monday game, Minnesota received 1.2 innings of one-hit, scoreless relief from Adams, 1.1 innings of one-hit, scoreless relief from Taylor Rogers and a home run and RBI from Brooks Lee. San Francisco got a 3-for-4 game with a home run and three RBIs from Gilbert, 2.2 hitless scoreless innings from Tristan Beck and a hitless scoreless inning from Trent Harris.

After this series, Minnesota will host Texas for three games starting Friday, Sept. 25. San Francisco will host the Los Angeles Dodgers for three games starting Friday.

Interstat’s game simulator projects a final score of Minnesota 4, San Francisco 3. Interstat’s ELO system gives San Francisco a 50.9 percent probability to win. Minnesota has been installed as the pregame favorite with a spread of -1.5. The over/under is 7.5.