SEATTLE (Interstat) — Yordan Alvarez hit a two-run homer and Isaac Paredes also went deep as the Houston Astros defeated the Seattle Mariners 7-0 on Tuesday, Sept. 22, 2026, at T-Mobile Park. Miguel Ullola earned the win, and Logan Gilbert took the loss. Houston outhit Seattle 12-4. The Astros scored one run in the first, three in the second, one in the fifth and two in the seventh. Alvarez added a run-scoring single. Christian Walker hit a three-run homer. Paredes finished 2 for 4 with a home run and an RBI. Jose Altuve had two hits. Cam Smith, Brice Matthews and Jeremy Peña each had a hit for Houston. Bennett Sousa struck out three over two scoreless innings, and Logan VanWey added two scoreless innings. AJ Blubaugh pitched a scoreless inning. The game took 3 hours, 3 minutes before an announced attendance of 33,382. Houston improved to 78-79, while Seattle fell to 73-84.