CHICAGO (Interstat) — The Chicago White Sox erased a four-run deficit with a four-run eighth inning and walked off with a 6-5 victory over the New York Yankees in 12 innings Wednesday night at Guaranteed Rate Field.

The White Sox won for the first time in the three-game series after dropping the first two contests. Chicago’s record improved to 56-51, while the Yankees fell to 61-47. Attendance was listed at 31,694, and the game lasted 3 hours, 43 minutes.

New York stormed ahead in the first inning against White Sox starter Davis Martin. Ben Rice led off with a double, and Jasson Domínguez walked. Paul Goldschmidt singled to left, scoring Rice and moving Domínguez to third. Spencer Jones then launched a three-run homer to left-center field, his third of the season, giving the Yankees a 4-0 lead.

Yankees starter Cam Schlittler dominated early, holding Chicago hitless through four innings. He finished with a line of 6 1/3 innings, two hits, one earned run and eight strikeouts. The only blemish came in the bottom of the seventh. With one out, Munetaka Murakami walked, Miguel Vargas was hit by a pitch, and Colson Montgomery popped out. Andrew Benintendi then doubled to right field, scoring Murakami and cutting the lead to 4-1. Schlittler was relieved after the double by Tim Hill, who struck out Braden Montgomery to end the inning.

The White Sox completed the comeback in the eighth. Against Yankees reliever Fernando Cruz, Chase Meidroth led off with a double off the glove of third baseman Ryan McMahon. After Edgar Quero popped out, Sam Antonacci crushed a two-run homer to right field, his eighth of the year, making it 4-3. Murakami followed with a solo homer to center, his 23rd, tying the game at 4.

Neither team scored in the ninth or 10th innings. In the top of the 11th, the Yankees regained the lead. With Ali Sánchez on third base after a double and a groundout, Anthony Volpe lifted a sacrifice fly to right field, scoring Sánchez and giving New York a 5-4 advantage.

Chicago answered in the bottom of the 11th. Facing Yankees reliever Camilo Doval, Murakami singled and moved to third on a groundout. After another groundout, Andrew Benintendi walked, and Braden Montgomery also walked to load the bases. Tristan Peters then grounded out to second, but not before the tying run scored on a fielder’s choice, making it 5-5.

The game ended in the bottom of the 12th. With one out, Peters reached on an error and advanced to second. Meidroth sacrificed him to third. Edgar Quero then singled to center field, scoring Peters and sealing the 6-5 win.

Jordan Hicks earned the win with a scoreless 12th inning, striking out one and allowing one hit. He improved to 1-1. Ryan Yarbrough took the loss for the Yankees, dropping to 2-1 after allowing one unearned run in one inning. White Sox relievers Grant Taylor, Chris Murphy, Trevor Richards and Hicks combined for 5 1/3 scoreless innings after Martin exited.

Spencer Jones led the Yankees offense with a 2-for-4 night, including the three-run homer and three RBIs. Antonacci and Murakami each homered for Chicago, with Antonacci driving in two runs.

The Yankees had nine hits, the White Sox six. New York scored four in the first and one in the 11th; Chicago scored one in the seventh, three in the eighth, one in the 11th and one in the 12th.

The most pivotal sequence occurred in the eighth inning, when the White Sox erased a four-run deficit on back-to-back home runs by Antonacci and Murakami, turning a 4-1 game into a 4-4 tie and setting the stage for extra innings.

The Interstat game simulator had projected a final score of New York 6, Chicago 5. Interstat’s ELO system gave the Yankees a 57.8 percent probability to win. New York was installed as a pregame favorite with a spread of minus-1.5. The total score of 11 went under the over-under line of 7.5.