PHILADELPHIA (Interstat) — Trea Turner hit a three-run homer during a five-run second inning and Alec Bohm added a two-run blast in the eighth as the Philadelphia Phillies defeated the Pittsburgh Pirates 10-6 on Wednesday night at Citizens Bank Park.

Attendance was 41,766, and the game lasted three hours, 18 minutes.

The Phillies improved to 49-38, while the Pirates fell to 43-44. Orion Kerkering earned the win, his sixth without a loss, after tossing one and two-thirds scoreless innings with no hits. Paul Skenes took the loss, dropping to 6-8.

Philadelphia erupted in the second inning against Skenes. Alec Bohm was hit by a pitch, and Bryson Stott singled. After a strikeout, Gabriel Rincones Jr. walked to load the bases. Justin Crawford reached on a fielder’s choice that scored Bohm and Stott, with Rincones moving to third and Crawford to second on a throwing error by third baseman Nick Gonzales. Turner followed by launching his tenth homer of the season to left, scoring Rincones and Crawford and giving the Phillies a 5-0 lead.

Pittsburgh answered in the third. Henry Davis led off with his seventh homer of the year to left-center. Konnor Griffin singled, and after a strikeout, Bryan Reynolds singled to left, scoring Griffin to cut the deficit to 5-2.

Philadelphia responded immediately in the bottom half. Brandon Marsh led off with his fifteenth homer, a solo shot to right, making it 6-2.

The Phillies added two more in the fourth. Rincones singled, and after a lineout, Turner singled. Kyle Schwarber struck out, but Bryce Harper doubled to center, scoring Rincones and Turner for an 8-2 lead.

Pirates starter Paul Skenes was lifted after four innings, having allowed eight runs, six earned, on seven hits with six strikeouts and two walks.

Pittsburgh climbed back in the fifth. Esmerlyn Valdez and Ryan O’Hearn singled. Nick Gonzales then singled to center, scoring Valdez. Jake Mangum was hit by a pitch to load the bases. Jared Triolo, pinch-hitting, was also hit by a pitch, forcing in O’Hearn and cutting the lead to 8-4.

Pirates reliever Cam Sanders worked one and two-thirds scoreless innings, allowing one hit with two strikeouts. Yohan Ramírez followed with one and one-third hitless innings, striking out four.

The Pirates inched closer in the seventh. Nick Gonzales walked, and Jake Mangum walked. Triolo doubled sharply to left, scoring both runners and bringing Pittsburgh within 8-6.

But the Phillies responded in the eighth. With one out, Marsh singled. Bohm then crushed his tenth homer of the season to center, scoring Marsh and giving Philadelphia a 10-6 advantage.

Pittsburgh went quietly in the ninth. Jhoan Duran pitched a scoreless inning with one strikeout, and Kerkering closed out the game.

For the Phillies, Zack Wheeler started and struck out ten over four and two-thirds innings but allowed nine hits and four earned runs. He left with the lead, but Kerkering got the decision. Kyle Backhus contributed two-thirds of a hitless inning with one strikeout.

For the Pirates, Skenes was tagged for eight runs, six earned, in four innings. Ramírez and Sanders combined for three scoreless innings of relief.

Trea Turner went two for five with a homer and three runs batted in. Brandon Marsh was two for four with a homer and an RBI. Triolo drove in three runs in a pinch-hit role. Bohm finished one for four with two RBIs. Wheeler fanned ten Pirates.

The Pirates and Phillies split the first two games of the series. Pittsburgh won Monday 11-7, and Philadelphia shut out the Pirates 8-0 on Tuesday. The series concludes Thursday.

Interstat’s game simulator had projected a final score of Philadelphia Phillies 7, Pittsburgh Pirates 5. Interstat’s ELO system had projected Philadelphia with a 62.10 percent probability to win. Philadelphia had been installed as a pregame favorite with a spread of -1.5. The total score of 16 went under the over/under line of 8.