NEW YORK (Interstat) — Gavin Williams pitched into the sixth inning, Kyle Manzardo collected three hits and the Cleveland Guardians beat the New York Yankees 5-4 on Wednesday night at Yankee Stadium II.

Williams allowed four hits and three earned runs over 5 1/3 innings, striking out six. He improved to 9-3 for the season. Cade Smith earned his 21st save despite allowing a run in the ninth, and Colin Holderman and Tim Herrin each contributed scoreless relief.

The Guardians, who evened their record at 36-27, got a balanced offensive attack. Rhys Hoskins drove in three runs with a home run and a single. Manzardo went 3 for 4 with a home run, two doubles and an RBI. Jose Ramirez also homered and singled twice, scoring three times.

Gerrit Cole took the loss for New York, allowing six hits and four earned runs over 5 1/3 innings with two strikeouts. The Yankees fell to 36-25.

Cleveland opened the scoring in the second inning when Manzardo crushed a solo home run to right field, his seventh of the season. The Yankees answered in the bottom half when Jazz Chisholm Jr. led off with a homer to right, also his seventh, tying the game 1-1.

The Guardians regained the lead in the fourth. Ramirez singled with one out, and after Chase DeLauter struck out, Hoskins launched a two-run homer to left field, his sixth, giving Cleveland a 3-1 lead. Angel Martinez followed with a double but was stranded.

New York cut the lead to 3-2 in the bottom of the fourth when Jose Caballero homered to left, his fifth, after a review upheld the call.

Cleveland stretched the lead in the sixth. Ramirez led off with a solo homer to right, his ninth, making it 4-2. Manzardo followed with a double and Hoskins walked, but a strikeout and a lineout ended the inning.

The Yankees trimmed the deficit to 4-3 in the bottom of the sixth. Ben Rice doubled and scored on a Cody Bellinger sacrifice fly.

The pivotal moment came in the eighth inning. Ramirez singled, and after DeLauter struck out, Manzardo doubled to center, putting runners at second and third. Hoskins then lined a single to left, scoring Ramirez and sending Manzardo to third. The inning ended when Martinez grounded into a double play, but the run gave Cleveland a 5-3 edge.

New York fought back in the ninth against Smith. Paul Goldschmidt led off with a double and scored on another sacrifice fly by Bellinger, cutting the lead to 5-4. But Smith struck out Chisholm and got Caballero to pop out to shortstop to end the game.

Attendance was 37,683, and the game lasted 2 hours, 37 minutes.

Manzardo was the top star for Cleveland, continuing a hot stretch. In his previous game Tuesday, he went 2 for 4 with a home run and two RBIs in a 9-4 win over the Yankees. After an 0-for-3 performance May 31 against Boston, he bounced back with a 2-for-4 game May 29.

The Guardians entered the game having won four of their last five, including a series win over Boston and a victory in the opener of this series Tuesday. The Yankees had won four of six before Wednesday, including a sweep of Kansas City and a series win at Oakland.

Cleveland’s pitching staff held the Yankees to five hits. Williams worked efficiently, getting through the first three innings with just one run allowed. Herrin retired the only batter he faced in the sixth, striking out Chisholm. Holderman pitched a perfect seventh with two strikeouts. Smith, despite the run, recorded his 21st save.

For New York, Fernando Cruz threw 1 1/3 scoreless innings with three strikeouts, and Paul Blackburn added 1 2/3 shutout frames. The Yankees had opportunities but left six runners on base.

The game featured three home runs and four doubles. Cleveland finished with nine hits, New York with five. Both teams played error-free defense.

Cleveland improved to 2-0 in the season series against New York, following Tuesday’s 9-4 win. The two teams meet again Thursday before Cleveland travels to Texas for a three-game set and then returns home to host the Yankees next week.

New York continues its homestand with a series against Boston beginning Friday.

Interstat’s game simulator had projected a final score of Cleveland 4, New York 7. Interstat’s ELO system gave the Yankees a 60.90 percent probability to win. New York had been installed as a pregame favorite with a spread of minus 1.5. The total score of 9 went under the over/under line of 7.