BLOOMINGTON, Minn. (Interstat) — The Minnesota Twins rallied from a three-run deficit with a grand slam and a four-run fifth inning to defeat the Chicago White Sox 9-6 on Monday night at Target Field.

Joe Ryan pitched six strong innings to earn his fourth win, and Tristan Gray delivered the decisive blow with a fourth-inning grand slam as the Twins snapped a four-game losing streak against the White Sox. Chicago had won three of the previous four meetings, including a 6-2 victory Thursday.

The White Sox struck first in the top of the first when Sam Antonacci reached on a fielding error by Gray, the shortstop. Miguel Vargas followed with a double to right field, putting runners on second and third with no outs. But Ryan regrouped, retiring Andrew Benintendi on a foul-tip strikeout, Colson Montgomery on a popout and Chase Meidroth on a swinging strikeout to escape the jam.

Minnesota drew first blood in the bottom of the inning against White Sox starter David Sandlin. Brooks Lee singled to right field, and Kody Clemens followed with a single that moved Lee to second. After Josh Bell struck out, Trevor Larnach ripped a line-drive single to center field, scoring Lee and sending Clemens to third. Austin Martin flied out to center to end the inning with the Twins leading 1-0.

The game remained 1-0 until the third inning. Rikuu Nishida led off with a bunt groundout, but Antonacci lined a double to right. Vargas flied out to right, allowing Antonacci to advance to third. Benintendi then singled to right, driving in Antonacci to tie the game 1-1. Montgomery struck out looking to end the inning.

Sandlin settled in after the first, but the Twins broke through again in the fourth. Bell led off with a double to right, and Larnach singled to shortstop, moving Bell to third. Martin grounded into a forceout, erasing Larnach at second but putting Martin on first. Victor Caratini then reached on a fielder’s choice as shortstop Montgomery cut down Bell at the plate. Luke Keaschall walked to load the bases, bringing Gray to the plate. Gray launched a 1-0 pitch over the right-center field wall for a grand slam, his fourth home run of the season, giving the Twins a 5-1 lead. Byron Buxton followed with a single, but Lee struck out looking to end the inning.

The White Sox answered immediately in the top of the fifth. Nishida singled to second, and Antonacci flied out to left. Vargas then crushed a two-run homer to left-center, his 14th, cutting the deficit to 5-3. Benintendi followed with a solo home run to right, his fifth, pulling Chicago even at 5-5. Montgomery struck out on a foul tip, and Meidroth flied out to left to end the inning.

The momentum swung back to Minnesota in the bottom of the fifth. Clemens walked, and Bell singled to right, moving Clemens to second. Larnach walked to load the bases. Martin singled to right, scoring Clemens and tying the game at 6-6. Caratini then singled to left, scoring Bell and giving the Twins a 7-6 lead. Keaschall followed with a sacrifice fly to right, scoring Larnach and extending the lead to 8-6. Gray added a sacrifice fly to third baseman Vargas in foul territory, scoring Martin for a 9-6 advantage. Buxton struck out looking to end the inning.

Sandlin took the loss, falling to 1-1. He allowed nine runs, eight earned, on nine hits and three walks over five innings, striking out five. Ryan improved to 4-3, surrendering four earned runs on eight hits while striking out nine and walking one over six innings.

The White Sox threatened in the ninth. With one out, Antonacci singled to right. Vargas then crushed his second homer of the game, a line drive to left field that brought Antonacci home and cut the score to 9-8. But Twins reliever Travis Adams, who entered after the homer, induced a groundout from Benintendi and struck out Montgomery swinging to end the game.

Adams earned a hold after allowing two earned runs on two hits in one inning. Kody Funderburk pitched a scoreless seventh, allowing no hits, and Yoendrys Gómez worked a scoreless eighth, surrendering one hit with a strikeout.

Attendance was 12,525, and the game lasted 2 hours, 32 minutes.

The White Sox fell to 32-28, while the Twins improved to 28-33. Chicago had won two straight and three of four entering the game, including a three-game sweep of the Detroit Tigers over the weekend. Minnesota had lost five of its previous six, including a three-game sweep at Pittsburgh.

Miguel Vargas led the White Sox offense, going 3 for 5 with two home runs, a double and four RBIs. Andrew Benintendi added two hits, including a home run and two RBIs. Sam Antonacci scored three times and had two hits.

For the Twins, Gray finished 1 for 3 with the grand slam and five RBIs. Josh Bell was 2 for 4 with a double and a run. Austin Martin drove in a run and scored once. The Twins executed two sacrifice flies.

The series continues Tuesday night at Target Field, with the White Sox scheduled to face the Twins again before traveling to Philadelphia for a weekend series against the Phillies. Minnesota will host Kansas City after the series with Chicago.

Interstat’s game simulator projected a final score of Chicago White Sox 6, Minnesota Twins 5. Interstat’s ELO system had given Minnesota a 52.20 percent probability to win. The Twins were installed as a pregame favorite with a spread of -1.5. The total score of 15 went under the over/under line of 7.5.