CHICAGO (Interstat) — Miguel Vargas delivered a walk-off two-run homer in the bottom of the 10th inning Friday night, lifting the Chicago White Sox to a 4-3 victory over the Detroit Tigers at Guaranteed Rate Field.

The game, which lasted 2 hours 29 minutes before an announced crowd of 30,019, saw the White Sox improve to 30-27 while the Tigers fell to 22-36. Chicago outhit Detroit 10-4.

Detroit struck first in the third inning. After Zack Short drew a walk, Dillon Dingler crushed an 11th home run of the season to left-center field, scoring Short and giving the Tigers a 2-0 lead.

The White Sox answered in the bottom of the third. Sam Antonacci singled, and after Munetaka Murakami grounded into a force out, Vargas doubled to left field to drive in Luisangel Acuña, making it 2-1.

Neither team scored again until the ninth inning. Detroit starter Troy Melton turned in a strong outing, allowing six hits and one earned run over seven innings with one strikeout. But the White Sox bullpen matched him, with Sean Newcomb throwing 2 2/3 scoreless innings, Brandon Eisert 1 1/3, Seranthony Domínguez a scoreless eighth and Bryan Hudson a scoreless ninth.

The Tigers carried a 2-1 lead into the bottom of the ninth. With one out, Andrew Benintendi singled off reliever Kyle Finnegan. Tristan Peters followed with a single, putting runners at the corners. Rikuu Nishida then laid down a sacrifice bunt, and a throwing error by first baseman Spencer Torkelson allowed Benintendi to score, tying the game 2-2.

Detroit regained the lead in the top of the 10th. With Matt Vierling placed at second base as the automatic runner, Zach McKinstry sacrificed him to third. Zack Short then lifted a sacrifice fly to right field, scoring Vierling and giving Detroit a 3-2 edge.

In the bottom of the 10th, White Sox catcher Drew Romo began the inning as the automatic runner at second. Antonacci struck out, Derek Hill grounded out, and Vargas stepped to the plate. He launched a 13th home run of the season to left-center field, scoring Romo and winning the game 4-3.

Vargas finished 2-for-5 with three RBIs and the game-winning homer. He entered the night in a mini-slump, having gone 1-for-15 in his previous four games, but delivered when it mattered most.

Dingler was 1-for-4 with two RBIs for Detroit. Riley Greene recorded two of the Tigers’ four hits.

Bryan Hudson earned the win, improving to 3-1 after pitching a perfect 10th inning with one strikeout. Drew Anderson took the loss for Detroit, falling to 2-2.

The Tigers have now lost seven of their last eight games, including a 7-1 defeat Thursday at home against the Los Angeles Angels. The White Sox have won three straight after taking two of three from the Minnesota Twins earlier in the week.

The series continues Saturday with the same two teams meeting again at Guaranteed Rate Field. Detroit then travels to Tampa Bay for a three-game series beginning Monday, while the White Sox head to Minnesota for a three-game set starting the same day. The Tigers return home June 5 to host Seattle, and Chicago visits Philadelphia for a three-game series beginning June 5.

Interstat’s game simulator projected a final score of Chicago White Sox 5, Detroit Tigers 2. Interstat’s ELO system gave the White Sox a 50.60 percent probability of winning. Detroit entered as a pregame favorite with a spread of minus-1.5. The total of seven runs went over the over-under line of 8.5.