CLEVELAND, Ohio (Interstat) — The Cleveland Guardians defeated the Boston Red Sox 4-3 on Friday night at Progressive Field, scoring all four runs in the first inning and holding on for the win.

Cleveland sent nine batters to the plate in the opening frame. Rhys Hoskins singled home José Ramírez before Angel Martínez’s single to center field scored two more runs, aided by a fielding error. Patrick Bailey’s sacrifice fly plated Kyle Manzardo to make it 4-0.

Boston responded in the fifth inning. Marcelo Mayer singled in Mickey Gasper, Caleb Durbin doubled to score Isiah Kiner-Falefa and Jarren Duran’s sacrifice fly brought home Mayer. The Red Sox loaded the bases later in the inning but failed to score again.

Colin Holderman (3-0) tossed 1 1/3 hitless innings for the win. Cade Smith struck out three in the ninth for his 20th save. Tyler Samaniego (0-3) took the loss.

Boston outhit Cleveland 11-10 but left eight runners on base. The Red Sox fell to 23-33, while the Guardians improved to 34-25. The two teams meet again Saturday. Attendance was 34,404. Time of game was 2:14.