| # | Date | Time | Opponent | Top Performer | Record | Score |
|---|---|---|---|---|---|---|
| 1 | 2026-08-16 | 6:00 PM ET | @ Dep. A Coruna | Marc Aguado 90min 1g | 0-0 | 1-1 D |
| 2 | 2026-08-22 | 6:00 PM ET | vs FC Barcelona | Ali Houary 64min yc | 0-1 | 0-5 L |
| 3 | 2026-08-27 | 6:00 PM ET | @ Real Racing | Buba Sangaré 84min 1g | 0-2 | 2-3 L |
| 4 | 2026-09-06 | 6:00 PM ET | vs Real Sociedad | Germán Valera 81min yc | 0-3 | 2-3 L |
| 5 | 2026-09-12 | 12:30 PM ET | @ Athletic | Víctor Chust 90min | 0-3 | 1-1 D |
| 6 | 2026-09-12 | 6:00 PM ET | @ Athletic | 0-3 | 0-0 D | |
| 7 | 2026-09-15 | 3:30 PM ET | vs RM Castilla | Abiel Osorio 90min 1g | 0-4 | 2-3 L |
| 8 | 2026-09-18 | 3:00 PM ET | @ Espanyol | Germán Valera 90min 1g | 1-4 | 3-1 W |
| 9 | 2026-10-11 | vs Celta Vigo | 1-4 | 0-0 D | ||
| 10 | 2026-10-17 | 6:00 PM ET | @ Villarreal | |||
| 11 | 2026-10-24 | Scheduled | @ Rayo Vallecano | |||
| 12 | 2026-10-24 | 6:00 PM ET | @ Rayo Vallecano | |||
| 13 | 2026-10-31 | 6:00 PM ET | vs Valencia | |||
| 14 | 2026-11-07 | 6:00 PM ET | vs Betis | |||
| 15 | 2026-11-21 | 6:00 PM ET | @ Levante | |||
| 16 | 2026-11-28 | 6:00 PM ET | vs Club Atletico de Madrid | |||
| 17 | 2026-12-05 | 6:00 PM ET | @ Osasuna | |||
| 18 | 2026-12-12 | 6:00 PM ET | vs Sevilla | |||
| 19 | 2026-12-19 | 6:00 PM ET | @ Alaves | |||
| 20 | 2027-01-02 | 6:00 PM ET | @ Malaga | |||
| 21 | 2027-01-09 | 6:00 PM ET | vs Getafe | |||
| 22 | 2027-01-16 | 6:00 PM ET | @ FC Barcelona | |||
| 23 | 2027-01-23 | 6:00 PM ET | vs Rayo Vallecano | |||
| 24 | 2027-01-30 | 6:00 PM ET | @ Betis | |||
| 25 | 2027-02-06 | 6:00 PM ET | vs Levante | |||
| 26 | 2027-02-13 | 6:00 PM ET | vs Dep. A Coruna | |||
| 27 | 2027-02-20 | 6:00 PM ET | @ Club Atletico de Madrid | |||
| 28 | 2027-02-27 | 6:00 PM ET | @ Real Sociedad | |||
| 29 | 2027-03-06 | 6:00 PM ET | vs Malaga | |||
| 30 | 2027-03-13 | 6:00 PM ET | vs Villarreal | |||
| 31 | 2027-03-20 | 6:00 PM ET | @ Sevilla | |||
| 32 | 2027-04-03 | 6:00 PM ET | vs Alaves | |||
| 33 | 2027-04-10 | 6:00 PM ET | @ Celta | |||
| 34 | 2027-04-17 | 6:00 PM ET | vs Osasuna | |||
| 35 | 2027-04-20 | 6:00 PM ET | @ Real Madrid | |||
| 36 | 2027-05-01 | 6:00 PM ET | vs Espanyol | |||
| 37 | 2027-05-08 | 6:00 PM ET | @ Getafe | |||
| 38 | 2027-05-15 | 6:00 PM ET | vs Athletic | |||
| 39 | 2027-05-22 | 6:00 PM ET | @ Valencia | |||
| 40 | 2027-05-29 | 6:00 PM ET | vs Real Racing |