MEDELLIN, Colombia (Interstat) — A pivotal Copa Colombia clash is set for Sunday as Atlético Nacional hosts archrival América de Cali at Estadio Atanasio Girardot.

The match is a classic Colombian fixture, with Nacional holding a significant edge as the home team. Statistical models heavily favor the hosts; Interstat’s game simulator projects a 2-1 victory for Nacional, while its ELO rating system gives them a 77.70 percent probability to win.

Current form in the domestic cup competition supports that projection. Atlético Nacional enters the match with a strong Copa Colombia record of 3-1-1 (W-L-D). In contrast, América de Cali has struggled for consistency in the tournament, posting a 6-5 record.

The teams played to a 1-1 draw in their most recent head-to-head meeting on Aug. 24.

América de Cali arrives with momentum from a 2-1 road victory over Junior on Oct. 2, a bright spot in an otherwise difficult season across all competitions, where they are 11-14-15.

Atlético Nacional last played on Oct. 9, securing a 1-0 win over Once Caldas. Their overall record this season sits at 10-11-13.

Kickoff is scheduled for Sunday, Nov. 2, 2025, in Medellin.