- 2025-05-10 1y Manchester City 0 at Southampton 0
- 2024-10-26 1y Southampton 0 at Manchester City 1
- 2023-04-08 3y Manchester City 4 at Southampton 1 Jack Grealish ENG-MAYP 90min
- 2023-01-11 3y Manchester City 0 at Southampton 2 Sékou Mara ENG-SOUZ 62min 1g
- 2022-10-08 4y Southampton 0 at Manchester City 4 João Pedro Cavaco Cancelo ENG-MAYP 70min 1g 1a
- 2022-01-22 4y Manchester City 1 at Southampton 1
- 2021-09-18 5y Southampton 0 at Manchester City 0
- 2021-03-10 5y Southampton 2 at Manchester City 5 Kevin De Bruyne ENG-MAYP 72min 2g
- 2020-12-19 5y Manchester City 1 at Southampton 0 Raheem Sterling ENG-MAYP 90min 1g
- 2020-07-05 6y Manchester City 0 at Southampton 1 Che Adams ENG-SOUZ 70min 1g
- 2019-11-02 6y Southampton 1 at Manchester City 2 Kyle Walker ENG-MAYP 90min 1g
- 2019-10-30 6y Southampton 1 at Manchester City 3 Sergio Leonel Agüero del Castillo ENG-MAYP 90min 2g
- 2018-12-30 7y Manchester City 3 at Southampton 1 David Josué Jiménez Silva ENG-MAYP 90min 1g
- 2018-11-04 7y Southampton 1 at Manchester City 6 Raheem Sterling ENG-MAYP 90min 2g
- 2018-05-13 8y Manchester City 1 at Southampton 0 Gabriel Fernando de Jesus ENG-MAYP 31min 1g
- 2017-11-29 8y Southampton 1 at Manchester City 2 Kevin De Bruyne ENG-MAYP 90min 1g
- 2017-04-15 9y Manchester City 3 at Southampton 0 Vincent Jean Mpoy Kompany ENG-MAYP 90min 1g
- 2016-10-23 10y Southampton 1 at Manchester City 1
- 2016-05-01 10y Manchester City 2 at Southampton 4 Sadio Mané ENG-SOUZ 90min 3g
- 2015-11-28 10y Southampton 1 at Manchester City 3 Kevin De Bruyne ENG-MAYP 90min 1g
- 2015-05-24 11y Southampton 0 at Manchester City 2 Sergio Leonel Agüero del Castillo ENG-MAYP 90min 1g
- 2014-11-30 11y Manchester City 3 at Southampton 0 Gaël Dimitri Clichy ENG-MAYP 90min 1g
- 2014-04-05 12y Southampton 1 at Manchester City 4 Samir Nasri ENG-MAYP 90min 1g
- 2013-12-07 12y Manchester City 1 at Southampton 1
- 2013-02-09 13y Manchester City 1 at Southampton 3 Steven Davis ENG-SOUZ 80min 1g
- 2012-08-19 14y Southampton 2 at Manchester City 3 Samir Nasri ENG-MAYP 90min 1g yc
- 2007-01-28 19y Southampton 1 at Manchester City 3
- 2005-01-01 21y Southampton 1 at Manchester City 2 Paul Bosvelt ENG-MAYP 90min 1g
- 2004-10-02 22y Manchester City 0 at Southampton 0
- 2004-04-17 22y Southampton 3 at Manchester City 1 Kevin Phillips ENG-SOUZ 90min 2g
- 2003-11-01 22y Manchester City 2 at Southampton 0 Paulo César Wanchope Watson ENG-MAYP 90min 1g
- 2003-05-10 23y Southampton 1 at Manchester City 0 Michael Lennart Svensson ENG-SOUZ 90min 1g
- 2002-10-04 24y Manchester City 0 at Southampton 2
- 2001-03-02 25y Southampton 1 at Manchester City 0
- 2000-10-22 26y Manchester City 2 at Southampton 0
- 1996-03-15 30y Southampton 1 at Manchester City 2
- 1996-01-30 30y Manchester City 1 at Southampton 1
- 1995-02-03 31y Manchester City 2 at Southampton 2
- 1994-04-03 32y Manchester City 1 at Southampton 0
- 1993-12-27 32y Southampton 1 at Manchester City 1
- 1993-04-30 33y Manchester City 1 at Southampton 0
- 1992-10-23 34y Southampton 0 at Manchester City 1
- 1992-03-14 34y Southampton 1 at Manchester City 0
- 1991-11-01 34y Manchester City 3 at Southampton 0
- 1989-12-09 36y Manchester City 1 at Southampton 2
- 1987-04-11 39y Southampton 4 at Manchester City 2
- 1986-11-01 39y Manchester City 1 at Southampton 1
- 1986-01-11 40y Southampton 0 at Manchester City 1
- 1985-09-07 41y Manchester City 0 at Southampton 3
- 1983-03-19 43y Manchester City 1 at Southampton 4